Port Wine Stain birthmarks remain a challenge to treat despite the development of laser technologies over the last 20 years. In this weeks show, host Dr Lycka talks with Dr Kristen Kelly, Associate Clinical Professor at the Beckman Laser Institute, University of California, Irvine. The two doctors discuss exactly what is a port wine stain birthmark, and provide an simple explanation of the challenges still encountered with port wine stain treatment and removal. The growing range and abilities of lasers to treat these is highlighted, along with the ongoing challenge of how to prevent port wine stains from developing again. Dr Kelly also outlines the leading edge research that she is involved with which is shaping the way in which port wine stains, and other blood vessel lesions, will be treated in the future.